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What is the difference between acute and chronic hepatitis C?

The main difference between them lies in the duration of the infection and its effect on the body

What is the difference between acute and chronic hepatitis C?

🔹 Acute hepatitis C develops within the first six months after infection with the virus. For many people, this period passes without noticeable symptoms, so they may be unaware of the infection. Sometimes symptoms such as weakness, nausea, loss of appetite, abdominal discomfort, dark urine, or yellowing of the skin and the whites of the eyes may appear. According to the CDC, most cases of acute hepatitis C do not have noticeable symptoms, and in more than half of those infected, the acute infection can become chronic.

🔹 Chronic hepatitis C means the virus remains in the body for more than six months. A chronic infection may not cause noticeable symptoms for years, but it gradually damages the liver. Without treatment, some people may develop fibrosis, cirrhosis, and other serious complications.

It’s important to remember: the presence of antibodies to hepatitis C does not necessarily confirm that the virus is currently present in the body. A positive antibody test result means that the person has been exposed to the virus at some point. To confirm an active infection, a test for hepatitis C viral RNA is required. Today, doctors don’t always wait for an acute infection to become chronic. Current guidelines recommend treating patients with a confirmed active infection using direct-acting antiviral drugs. In most cases, this treatment lasts 8–12 weeks and helps cure more than 95% of patients.

💙 Hepatitis C may remain asymptomatic for a long time. That is why testing is an important step toward timely treatment and preserving liver health.

You can find out where to get tested for hepatitis C in Germany here